Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-28T04:48:56.001Z Has data issue: false hasContentIssue false
  • English
  • Français

Chloral hydrate and middle ear pressure

Published online by Cambridge University Press:  29 June 2007

Khader J. Abdul-Baqi
Khader J. Abdul-Baqi*
Affiliation:
Amman, Jordan
*
Dr Khader J. Abdul Baqi, University of Jordan, P. O. Box 13001 Amman, Jordan.
Get access Rights & Permissions [Opens in a new window]

Abstract

Middle ear pressure and tympanic membrane compliance were measured in 34 infants and young children (66 ears) with normal middle ears under oral choral hydrate hypnosis. Tympanograms were performed before and 40 to 60 minutes after administration of the drug. Results showed that the middle ear pressure increased significantly in all cases and in both sexes. This increase ranged between +19 and +219 mm H2O. In all cases the pressure returned to its prehypnotic values after recovery. Results of tympanic membrane compliance showed significant increase in males and not significant decrease in females.

Keywords

Chloral hydrateAcoustic impedance tests
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 6 , June 1991 , pp. 421 - 423
Copyright
Copyright © JLO (1984) Limited 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cabana, B. E., Gessner, P. K. (1970) The kinetics of chloral hydrate metabolism in mice and the effect thereon of ethanol. Journal of Pharmacology and Experimental Therapeutics, 174: 260–275.Google ScholarPubMed
Devis, I., Moore, J. R. M., Lahiri, S. K. (1979) Nitrous oxide and the middle ear. Anaesthesia, 34: 147–151.CrossRefGoogle Scholar
DiPalma, J. R. (1971) Drill's pharmacology in medicine (4th ed.) New York: McGraw Hill.Google Scholar
King, K. (1963) Chloral hydrate (Noctec) overdose. Medical Journal of Australia, 2: 260.CrossRefGoogle Scholar
Laurence, D. R., Bennett, P. N. (1980) Clinical Pharmacology (5th ed.) New York: Churchill Livingstone, p. 331.Google Scholar
Patterson, M. E., Bartlett, P. C. (1976) Hearing impairment caused by intra-tympanic pressure changes during general anaesthesia. Laryngoscope, 86: 399–404.CrossRefGoogle Scholar
Rasmussen, P. E. (1967) Middle ear and maxillary sinus during nitrous oxide anaesthesia. Acta Otolaryngologica, 63: 7–16.CrossRefGoogle Scholar
Richards, S. H., O'Neill, G., Wilson, F. (1982) Middle ear pressure variations during general anaesthesia. Journal of Laryngology and Otlogy, 96: 883–892.CrossRefGoogle ScholarPubMed
Singh, C. B., Kirk, R. (1979) The effect of nitrous oxide on middle ear pressure in children during anaesthesia. Journal of Laryngology and Otology, 93: 349–356.CrossRefGoogle ScholarPubMed
Thomsen, K. A., Terkildsen, K., Arnfred, I. (1965) Middle ear pressure variations during anaesthesia. Archives of Otolaryngology, 82: 609–611.CrossRefGoogle Scholar
Waun, J. E., Swietzer, R. S., Hamilton, W. K. (1967) Effect of nitrous oxide on middle ear mechanics and hearing acuity. Anaesthesiology, 28: 846–850.CrossRefGoogle ScholarPubMed