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Diagnostic imaging of the larynx: autofluorescence of laryngeal tumours using the helium-cadmium laser

Published online by Cambridge University Press:  29 June 2007

Meredydd Lloyd Harries ,
Stephen Lam ,
Calum MacAulay ,
Jianan Qu  and
Branko Palcic
Meredydd Lloyd Harries*
Affiliation:
Fellow in Phonosurgery, Vancouver General Hospital.
Stephen Lam
Affiliation:
British Columbia Cancer Agency, Vancouver, Canada.
Calum MacAulay
Affiliation:
British Columbia Cancer Agency, Vancouver, Canada.
Jianan Qu
Affiliation:
British Columbia Cancer Agency, Vancouver, Canada.
Branko Palcic
Affiliation:
British Columbia Cancer Agency, Vancouver, Canada.
*
Address for correspondence: Mr M. L. Harries, The Voice Clinic, Royal National Throat, Nose and Ear Hospital, 330 Gray's Inn Road, London WCIX 8DA.
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Abstract

The use of tissue autofluorescence for the detection and localization of cancer of the larynx is described. In this pilot study, eight patients with probable carcinoma of the vocal folds underwent laryngoscopy in which the tissue autofluorescence spectra of normal and pathologically confirmed tumour tissue were acquired in vivo. Fluorescence images of the suspect areas were also acquired using the LIFE system (Xillix Technologies Corp.). The results suggest that the autofluorescence properties of laryngeal tissue, under 442 nm illumination, are similar to those of bronchial tissue and that the LIFE system has the potential to increase the accuracy of staging of cancer of the larynx and also to allow earlier diagnosis of tumours and theirrecurrence

Keywords

Laryngeal neoplasmsLasers
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 109 , Issue 2 , February 1995 , pp. 108 - 110
Copyright
Copyright © JLO (1984) Limited 1995

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