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Hearing impairment and facial palsy as initial signs of Wegener's granulomatosis

Published online by Cambridge University Press:  29 June 2007

I. H. Calonius  and
C. K. Christensen
I. H. Calonius
Affiliation:
Department of Gynaecology and Obstetrics, Silkeborg Centralsygehus, 8600 Silkeborg, Denmark.
C. K. Christensen
Affiliation:
Department of Otorhinolaryngology, University Hospital, Aarhus, Denmark.
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Summary

In two patients with Wegener's granulomatosis, treatment-resistant serous otitis media was followed by unilateral facial nerve palsy. Later both patients developed uraemia due to extracapillary glomerulonephritis. In one of them, who was treated with prednisone and cyclophosphamide, renal function improved, while in the other patient it remained impaired. Both patients suffered lasting hearing impairment in spite of general improvement during the course of the disease. The facial nerve palsy improved slightly in one, while no improvement was seen in the other.

The possibility of Wegener's granulomatosis or other autoimmune collagen diseases should be considered in cases of treatment-resistant serous otitis media. Early diagnosis and treatment can possibly save the patient from the lifethreatening consequences of these diseases.

Type
Clinical records
Information
The Journal of Laryngology & Otology , Volume 94 , Issue 6 , June 1980 , pp. 649 - 657
Copyright
Copyright © JLO (1984) Limited 1980

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