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Impact of gender on clinical presentation of chronic rhinosinusitis with and without polyposis

Published online by Cambridge University Press:  10 January 2008

N Y Busaba ,
H-J Sin  and
S D Salman
N Y Busaba*
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA Division of Otolaryngology, VA Boston HealthCare System, Boston, Massachusetts, USA Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
H-J Sin
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
S D Salman
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
*
Address for correspondence: Dr Nicolas Y Busaba, Department of Otolaryngology–Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston MA 02114, USA. Fax: +1 617 573 3914 E-mail: nicolas_busaba@meei.harvard.edu
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Abstract

Study objective:

To determine the impact of a patient's gender on the clinical presentation of chronic rhinosinusitis with and without nasal polyposis.

Study design and methods:

Prospective study of 514 adult patients who presented with chronic rhinosinusitis with and without nasal polyposis. The patients were divided into two groups based on gender: female (n = 273) and male (n = 241). The following data were collected: presenting symptoms, co-morbidities, nasal endoscopy and sinus computed tomography findings, diagnosis, and outcome of surgery. Statistical analysis was performed using the chi-square test, with statistical significance set at p < 0.05.

Results:

Facial pain and headache were more prevalent among women, while nasal obstruction was more prevalent among men (p < 0.05). There was no statistically significant difference in the prevalence of environmental allergy, asthma, psychiatric illness or anatomical variants obstructing the osteomeatal unit, comparing the genders. Chronic rhinosinusitis without polyposis was the more common diagnosis among women, while chronic rhinosinusitis with polyposis was the more common diagnosis among men (p < 0.05). Following surgery, a higher percentage of male patients reported improvement in nasal obstruction (p < 0.05), but there was no statistically significant difference in the improvement of the other presenting symptoms, comparing the genders.

Conclusion:

Women who suffer from chronic rhinosinusitis are more likely to complain of facial pain or headache on presentation and to be diagnosed with chronic rhinosinusitis without polyposis. On the other hand, men are more likely to complain of nasal obstruction, to be diagnosed with chronic rhinosinusitis with polyposis, and to report improvement in nasal obstruction following surgery.

Keywords

SinusitisNasal PolypsSex Factors
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 11 , November 2008 , pp. 1180 - 1184
Copyright
Copyright © JLO (1984) Limited 2008

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References

1 Baumann, I, Blumenstock, G. Impact of gender on general health-related quality of life in patients with chronic sinusitis. Am J Rhinol 2005;19:282–7CrossRefGoogle ScholarPubMed
2 Lyngberg, AC, Rasmussen, BK, Jorgensen, T, Jensen, R. Has the prevalence of migraine and tension-type headache changed over a 12-year period? A Danish population survey. Eur J Epidemiol 2005;20:243–9CrossRefGoogle Scholar
3 Lyngberg, AC, Rasmussen, BK, Jorgensen, T, Jensen, R. Incidence of primary headache: a Danish epidemiologic follow-up study. Am J Epidemiol 2005;161:1066–73CrossRefGoogle ScholarPubMed
4 Hung, CI, Wang, SJ, Hsu, KH, Juang, YY, Liu, CY. Risk factors associated with migraine or chronic daily headache in out-patients with major depressive disorder. Acta Psychiatr Scand 2005;111:310–15CrossRefGoogle ScholarPubMed
5 Wieringa, MH, Weyler, JJ, Van Bever, HP, Nelen, VJ, Vermeire, PA. Gender differences in respiratory, nasal and skin symptoms: 6-7 versus 13-14-year-old children. Acta Paediatr 1999;88:147–9CrossRefGoogle ScholarPubMed
6 Phillips Bute, B, Mathew, J, Blumenthal, JA, Welsh-Bohmer, K, White, WD, Landolfo, K et al. Female gender is associated with impaired quality of life 1 year after coronary artery bypass surgery. Psychosom Med 2003;65:944–951CrossRefGoogle ScholarPubMed
7 Lee, OY, Mayer, EA, Schmulson, M, Chang, L, Naliboff, B. Gender-related differences in IBS symptoms. Am J Gastroenterol 2001;96:2184–93CrossRefGoogle ScholarPubMed
8 Gliklich, RE, Metson, R. The health impact of chronic sinusitis in patients seeking otolaryngologic care. Otolaryngol Head Neck Surg 1995;113:104–9CrossRefGoogle ScholarPubMed
9 Piccirillo, JF, Merritt, MG Jr, Richards, ML. Psychometric and clinimetric validity of the 20-item Sino-Nasal Outcome Test (SNOT-20). Otolaryngol Head Neck Surg 2002;126:41–7CrossRefGoogle ScholarPubMed
10 Catalano, P, Roffman, E. Outcome in patients with chronic sinusitis after the minimally invasive sinus technique. Am J Rhinol 2003;17:17–22CrossRefGoogle ScholarPubMed
11 Barton-Donovan, LK, Blanchard, EB. Psychosocial aspects of chronic daily headache. J Headache Pain 2005;6:30–9CrossRefGoogle ScholarPubMed