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Orbital and skin metastases in a polymorphous low grade adenocarcinoma of the salivary gland

Published online by Cambridge University Press:  29 June 2007

K. M. Thomas*
Affiliation:
Departments of Histopathology and ENT, Whipps Cross Hospital, Whipps Cross Road, Leytonstone, London.
V. L. Cumberworth
Affiliation:
Departments of Histopathology and ENT, Whipps Cross Hospital, Whipps Cross Road, Leytonstone, London.
J. McEwan
Affiliation:
Departments of Histopathology and ENT, Whipps Cross Hospital, Whipps Cross Road, Leytonstone, London.
*
Dr K. M. Thomas, Department of Histopathology, Whipps Cross Hospital, Whipps Cross Road, Leytonstone, London E11 1NR.

Abstract

We report the previously undocumented development of an orbital metastasis and skin metastases in a patient with polymorphous low grade adenocarcinoma (PLGA) 15 years after initial presentation. The clinical course, treatment and changing histological features are discussed.

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1995

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References

Aberle, A. M., Abrams, A. M., Bowe, R., Melrose, R. J.,Handlers, J. P. (1985) Lobular (polymorphous low-grade) carcinoma of minor salivary glands. A clinicopathological study of twenty cases. Oral Pathology 60: 387395.CrossRefGoogle ScholarPubMed
Batsakis, J. G., Pinkston, G. R., Luna, M. A., Byers, R. M., Sciubba, J. J., Tillery, G. W. (1983) Adenocarcinomas of the oral cavity: a clinicopathological study of terminal duct carcinomas. Journal of Laryngology and Otology 97: 825835.CrossRefGoogle ScholarPubMed
Freedman, P. D., Lumerman, H. (1983) Lobular carcinoma of intraoral minor salivary glands. Oral Surgery, Oral Medicine, Oral Pathology 56: 157165.CrossRefGoogle Scholar
Luna, M. A., Batsakis, J. G., Nelson, G., Ordonez, N. G., Mackay, B., Tortoledo, M. E. (1987) Salivary gland adenocarcinomas. A clinicopathologic analysis of three distinctive types. Seminars in Diagnostic Pathology 4: (2) 117135.Google ScholarPubMed
Miliauskas, J. R. (1991) Polymorphous low-grade (terminal duct) adenocarcinoma of the parotid gland. Histopathology 19: 555557.CrossRefGoogle ScholarPubMed
Seifert, G. in collaboration with Sobin, L. H. and Pathologists in six countries (1992) World Health Organization, Histological typing of Salivary Gland Tumours 22.CrossRefGoogle Scholar
Shootweg, P. J., Muller, H. (1987) Low-grade adenocarcinoma of the oral cavity. A comparison between the terminal duct and papillary type. Journal of Cranio-Maxillo-Facial Surgery 15: 359364.CrossRefGoogle Scholar
Simpson, R. H. W., Clarke, T. J., Sarsfield, P. T. L., Gluckman, P. G. C., Balenjews, A. V. (1991) Polymorphous low grade adenocarcinoma of the salivary gland; a clinico-pathological comparison with adenoid cystic carcinoma. Histopathology 19 (2): 121129.CrossRefGoogle Scholar
Tay, H. L., Reilly, P. G., Akosa, A. B. (1992) Salivary terminal duct carcinoma. Journal of Laryngology and Otology 106: 649651.CrossRefGoogle ScholarPubMed
Tortoledo, M. E., Luna, M. A., Batsakis, J. G. (1984) Carcinoma ex-pleomorphic adenoma and malignant mixed tumours. Archives of Otolaryngology 110: 172176.CrossRefGoogle Scholar
Wenig, B. M., Gnepp, D. R. (1991) Polymorphous low grade adenocarcinoma of minor salivary glands. In Surgical Pathology of the Salivary Glands (Ellis, G. L., Auclair, P. L. and Gnepp, D. R., eds), W. B. Saunders Co., Philadelphia pp 390391.Google Scholar