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Sinonasal hybrid tumour involving the anterior skull base

Published online by Cambridge University Press:  12 July 2007

A Mazita ,
B S Gendeh  and
A I Zainal
A Mazita*
Affiliation:
Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
B S Gendeh
Affiliation:
Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
A I Zainal
Affiliation:
Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
*
Address for correspondence: Dr Mazita Ami, Department of ORL-HNS, Faculty of Medicine, Hospital Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Kuala Lumpur, Malaysia. Fax: 603 91737840 E-mail: mazitaami@yahoo.com
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Abstract

Objective:

We report a rare case of sinonasal hybrid tumour within an inverted papilloma.

Method:

The patient's case history and course of management are presented. The relevant medical literature are reviewed and discussed.

Results:

A 60-year-old man presented with unilateral nasal obstruction associated with anosmia. An ENT examination revealed a unilateral, left nasal mass. A provisional diagnosis of inverted papilloma was made. The patient underwent a transnasal endoscopic excision of the tumour, which was unfortunately complicated by a cerebrospinal fluid leak. Further treatment of this patient is described. We highlight the features of associated malignancy in inverted papilloma, and the importance of thorough histopathological examination of tissue specimens.

Conclusion:

Treatment of inverted papilloma with limited involvement of the skull base can be successfully achieved by endoscopic excision. A high index of clinical suspicion, together with meticulous histopathological examination, will enable diagnosis of associated malignancy. This will ensure that appropriate adjuvant treatment is given, resulting in a good clinical outcome.

Keywords

Hybrid TumourInverted PapillomaParanasal Sinus NeoplasmsEndoscopes
Type
Clinical Record
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 8 , August 2008 , pp. 861 - 863
Copyright
Copyright © JLO (1984) Limited 2008

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Footnotes

Presented at the 26th International Symposium on Infection and Allergy of the Nose. 1–4 February 2007, Kuala Lumpur, Malaysia.

References

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