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T-cell-rich histiocyte-rich B-Cell lymphoma of parotid gland

Published online by Cambridge University Press:  29 June 2007

W. G. McCluggage ,
D. McManus ,
P. Maxwell  and
M. Y. Walsh
W. G. McCluggage*
Affiliation:
Department of Pathology, Royal Group of Hospitals Trust, Belfast
D. McManus
Affiliation:
Department of Pathology, Royal Group of Hospitals Trust, Belfast The Queen's University of Belfast, Northern Ireland, UK
M. Y. Walsh
Affiliation:
Department of Pathology, Royal Group of Hospitals Trust, Belfast
*
Dr W. G. McCluggage, Department of Pathology, Royal Group of Hospitals Trust, Grosenor Road, Belfast BT12 6BL Fax: 01232 233643.
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Abstract

We describe a malignant lymphoma of the parotid gland arising in a patient with Sjögren's syndrome. Diagnosis was established on needle biopsy which showed a mixed population of lymphoid cells. Immunohistochemistry revealed B-lymphoid cells, T-lymphoid cells and histiocytes. Clonal immunoglobulin heavy chain gene rearrangement was demonstrated using the polymerase chain reaction. Within the confines of the small biopsy, the lesion qualifies for the designation T-cell-rich histiocyte-rich B-cell lymphoma. The value of molecular techniques in the diagnosis of malignant lymphoma on limited tissue samples is highlighted by this case.

Keywords

Parotid glandLymphoma, B-cell, T-cell, large cellImmuniohistochemistryPolymerase chain reaction
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 8 , August 1996 , pp. 811 - 813
Copyright
Copyright © JLO (1984) Limited 1996

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