Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-26T07:48:40.331Z Has data issue: false hasContentIssue false

“The King of Terrors” Revisited: The Smallpox Vaccination Campaign and its Lessons for Future Biopreparedness

Published online by Cambridge University Press:  01 January 2021

Extract

“Smallpox was always present, filling the churchyard with corpses, tormenting with constant fear all whom it had not yet stricken, leaving on those whose lives it spared the hideous traces of its power, turning the babe into a changeling at which the mother shuddered, and making the eyes and cheeks of the betrothed maiden objects of horror to the lover.” In 1848, British historian T.B. Macaulay first captured the picture of the devastation smallpox wreaked on its victims, but the “King of Terrors,” as it was dubbed by future president John Adams, had already decimated populations in the ancient world from Greece to Egypt to China. Smallpox had no respect for authority: the earliest identified victim, Pharaoh Ramses V (d.1157 B.C.) was but the first in a long line of monarchs and rulers who succumbed,. including the Hittite king Suppiluliumas I, Aztec Emperor Cuitlahuac, and Queen Mary II of England.

Type
Article
Copyright
Copyright © American Society of Law, Medicine and Ethics 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

John Adams referred to smallpox as the “King of Terrors.” McCullough, D., John Adams (New York: Simon and Shuster, 2000): At 141.Google Scholar
Koplow, D.A., Smallpox: The Fight to Eradicate a Global Scourge (Berkeley: University of California Press, 2003): At 10, citing T.B. Macaulay.Google Scholar
McCullough, , supra note 1, at 142–43.Google Scholar
Koplow, , supra note 2, at 1113. On Cuitlahuac, see Enriquez, J. Tang Yeh, C. Martinez, R., “SARS, Smallpox, and Business Unusual,” Harvard Business School Working Paper (draft), July 2003: At 7.10.1016/S1473-8325(03)00022-1CrossRefGoogle Scholar
Koplow, , supra note 2, at 1314.Google Scholar
Butterfield, L.H. Friedlander, M. Kline, M., eds., The Book of Abigail and John: Selected Letters of the Adams Family 1762–1784 (Cambridge, Mass.: Harvard University Press, 1975): At 137.Google Scholar
Koplow, , supra note 2, at 18.Google Scholar
Ewald, P.W., Plague Time (New York: Oxford University Press, 2000): At 179.Google Scholar
Id. at 103.Google Scholar
Alexander, J.T., Catherine the Great: Life and Legend (New York: Oxford University Press, 1989): At 147.Google Scholar
Id. at 147–48.Google Scholar
Koplow, , supra note 2, at 18.Google Scholar
Butterfield, L.H., ed. Diary and Autobiography of John Adams: Vol. 3 (Cambridge: Harvard University Press: 1961): At 280; McCullough, , supra note 1, at 142–44 (on the effects of variolation).Google Scholar
Koplow, , supra note 2, at 1819.10.4039/Ent1918-1CrossRefGoogle Scholar
Id. at 19.Google Scholar
Preston, R., “The Demon in the Freezer (New York: Random House, 2002): At 102–03.Google Scholar
For example, President Clinton discussed the issue in his May 1999 commencement address at the Naval Academy in Annapolis, Maryland.Google Scholar
O’Toole, T. Mair, M. Inglesby, T.V., “Shining Light on ‘Dark Winter,’” Clinical Infectious Diseases 34 (2002): 972983, available at <http://www.journals.uchicago.edu/CID/journal/issues/v34n7/020165/020165.web.pdf>.10.1086/339909CrossRefGoogle Scholar
Id. at 1213.Google Scholar
Nunn’s testimony is quoted by The Center for Civilian Biodefense Studies, at <http://www.hopkins-biodefense.org/darkwinter.html> (last visited October 1, 2003).+(last+visited+October+1,+2003).>Google Scholar
This phenomenon, known as Multiple Idiopathic Physical Symptoms (MIPS) was the subject of a conference held at Georgetown University on June 12, 2003—under the auspices of the Life Science and Society Initiative and the Imaging Science and Information Systems (ISIS) center. The proceedings of the conference will be published with support from the CDC.Google Scholar
Orenstein, W., Smallpox: Lessons from the Past, Strategies for the Future, Clouded by Uncertainty, presented at Smallpox Preparedness and Adverse Effects Management Working Session, Georgetown University, March 3, 2003 (publication forthcoming).Google Scholar
“Smallpox Fiasco,” Washington Post, July 14, 2003, at A20–21 (editorial). “Are We Ready?,” Washington Post, July 13, 2003, at B06 (editorial); Heil, E., Panel Questions HHS on Low Smallpox Vaccinations, available at <http://www.govexec.com/dailyfed/0703/072403cd2.htm> (July 24, 2003).+(July+24,+2003).>Google Scholar
President Delivers Remarks on Smallpox, (White House press release), at <http://www.whitehouse.gov/news/releases/2002/12/20021213–7.html> (December 13, 2002).+(December+13,+2002).>Google Scholar
Maj. Gen. J. Parker, Threat Assessment and Uncertainty, presented at Smallpox Preparedness and Adverse Effects Management Working Session, Georgetown University, March 3, 2003 (publication forthcoming).Google Scholar
At the Georgetown Conference on Smallpox on March 3, 2003, Dr. C. Everett Koop commented on the volumes of information on the smallpox vaccine and its potential side effects, noting the difficulty a layman could potentially have with sorting through the data on the CDC website to find information or to communicate.Google Scholar
Graham, B., Vaccinia Vaccine and the Biology of Adverse Effects Management, presented at Smallpox Preparedness and Adverse Effects Management Working Session, Georgetown University, March 3, 2003 (publication forthcoming).Google Scholar
Connolly, C., “Cardiac Cases Raise New Vaccination Questions,” Washington Post, March 27, 2003, at A12.Google Scholar
Connolly, , supra; Connolly, C., “Second Vaccinated Worker Dies of Heart Attack,” Washington Post, March 28, 2003, at A09.; Connolly, C., “Two States Halt Smallpox Shots,” Washington Post, March 29, 2003, at A07.Google Scholar
Miller, H.I., “A Shot in the Dark,” San Francisco Chronicle, March 12, 2003; Connolly, C., “Lawmakers, White House Agree on Smallpox Compensation,” Washington Post, April 11, 2003 at A11.Google Scholar
The vaccine carries the cowpox virus, creating the slim risk that during the incubation period, the virus might infect others.Google Scholar
Rawls, J., A Theory of Justice (Cambridge: Harvard University Press, 1971): At 313, 343.Google Scholar
Gostin, L.O., “Public Health Law In an Age of Terrorism: Rethinking Individual Rights and Common Goods,” Health Affairs, 21, no.6 (2002): At 86, 9091.10.1377/hlthaff.21.6.79CrossRefGoogle Scholar
Schneider, C.P. Gostin, L.O., “Reining in the King of Terrors” (unpublished editorial submitted to the Washington Post in March of 2003, on file with author (CS); Connolly, C., “Smallpox Campaign Taxing Health Resources,” Washington Post, March 10, 2003 at A04.Google Scholar
Weinstock, M., “Big Shot,” Government Executive, July 15, 2003, at 6, available at <http://www.govexec.com/features/0703/0703s3.htm>..>Google Scholar
The Technical Reference Model is available through the Federal Enterprise Architecture Program Management Office, at <http://www.feapmo.gov/feaTrm2.asp> (last visited October 1, 2003).+(last+visited+October+1,+2003).>Google Scholar
U.S. Department of Health and Human Services, et al.,, Information for Health: A Strategy for Building the National Health Information Infrastructure, Report and Recommendations from the National Committee on Vital and Health Statistics, available at <http://ncvhs.hhs.gov/nhiilayo.pdf> (November 15, 2001).+(November+15,+2001).>Google Scholar