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From Mad Cows to Neurotic Yeast: Novel Molecular Approaches to Understand Neurodegeneration

Published online by Cambridge University Press:  03 October 2008

T.F. Outeiro
T.F. Outeiro
Affiliation:
Cell and Molecular Neuroscience Unit, Instituto de Medicina Molecular, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal. Email: touteiro@gmail.com

Abstract

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Aging is the major known risk factor for Alzheimer's disease (AD) and Parkinson's disease (PD), but genetic deffects have been associated with familial cases. Huntington's disease (HD) is a purely genetic neurodegenerative disorder, where mutations in the IT15 gene, encoding for the protein huntingtin, determine the development of the disease. The Prion diseases differ from these other disorders because they can also have infections origin.

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Abstract
Information
Microscopy and Microanalysis , Volume 14 , Supplement S3 , September 2008 , pp. 105 - 106
Copyright
Copyright © Microscopy Society of America 2008