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Mass spectrometry inside single proteins by atom probe tomography

Published online by Cambridge University Press:  05 August 2019

Shi Qiu ,
Changxi Zheng ,
Vivek Garg ,
Jian Li ,
Ross K.W. Marceau  and
Jing Fu
Shi Qiu
Affiliation:
Department of Mechanical and Aerospace Engineering, Monash University, Clayton, VIC 3800, Australia
Changxi Zheng
Affiliation:
ARC Centre of Excellence for Future Low-Energy Electronics Technologies, Monash University, Clayton, VIC 3800, Australia School of Physics and Astronomy, Monash University, Clayton, VIC 3800, Australia
Vivek Garg
Affiliation:
Department of Mechanical and Aerospace Engineering, Monash University, Clayton, VIC 3800, Australia IITB-Monash Research Academy, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India
Jian Li
Affiliation:
Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia Department of Microbiology, Monash University, Clayton, VIC 3800, Australia
Ross K.W. Marceau*
Affiliation:
Deakin University, Institute for Frontier Materials, Geelong, VIC 3216, Australia
Jing Fu*
Affiliation:
Department of Mechanical and Aerospace Engineering, Monash University, Clayton, VIC 3800, Australia
*
*Corresponding authors. Email: ross.marceau@deakin.edu.au or jing.fu@monash.edu
*Corresponding authors. Email: ross.marceau@deakin.edu.au or jing.fu@monash.edu

Abstract

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Type
Recent Developments in Atom Probe Tomography
Information
Microscopy and Microanalysis , Volume 25 , Supplement S2 , August 2019 , pp. 334 - 335
Copyright
Copyright © Microscopy Society of America 2019 

References

[1]Kelly, T. F., Miller, M. K., Atom probe tomography. Review of Scientific Instruments 78, 031101 (2007).Google Scholar
[2]Granier, T., Gallois, B., Dautant, A., Langlois d'Estaintot, B., Precigoux, G., Comparison of the structures of the cubic and tetragonal forms of horse - spleen apoferritin. Acta Crystallographica Section D 53, 580-587 (1997).Google Scholar
[3]Schreiber, D. K., Perea, D. E., Ryan, J. V., Evans, J. E., Vienna, J. D., A method for site-specific and cryogenic specimen fabrication of liquid/solid interfaces for atom probe tomography. Ultramicroscopy 194, 89-99 (2018).Google Scholar
[4]The authors acknowledge funding from the Australian Research Council (DP180103955) and also the contributions from Drs Yu Chen, Gediminas Gervinskas and Michelle Dunstone. This work was performed in part at the Melbourne Centre for Nanofabrication (MCN), Victorian Node of the Australian National Fabrication Facility (ANFF). Also, the authors acknowledge the use of facilities within the Monash Centre for Electron Microscopy (MCEM), Monash Ramaciotti Cryo-EM platform, Monash Campus Cluster (MCC), and Deakin University's Advanced Characterisation Facility.Google Scholar