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Published online by Cambridge University Press: 14 March 2018
Most objects in our world are 3-dimensionai (3-D), and this is certainly true of cellular ultrastructure. The challenge in microscopy has always been how to analyze this 3-D information. Traditional thin-section microscopy has a minimal ability to view 3-D structure, because it is limited to viewing thin, almost twodimensional (2-D) planes taken from the specimen. The development of high and intermediate voltage electron microscopes (HVEM and IVEM) provides the ability to investigate the ultrastructure of thick biological samples—allowing a unique view of the 3-D interrelationships of cells and organelles.
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* TACT is copyrighted by Wake Forest University School of Medicine. TACT requires a 486 or better PC running Windows (95, NT 4.0, or higher) and sufficient RAM to handle large image files. The program is still in the developmental stages. Anyone interested in working with the program for research purposes or in commercial applications is encouraged to contact Dr. Jay Jerome (jjerome@wfubmc.edu) or Wake Forest University's Technology Asset Management Office (in care of Dr. William H. Williams, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157.
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