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Confocal Laser Microscopy on Biofilms: Successes and Limitations

Published online by Cambridge University Press:  14 March 2018

Betsey Pitts*
Affiliation:
Center for Biofilm Engineering, Montana State University, Bozeman, Montana
Philip Stewart
Affiliation:
Center for Biofilm Engineering, Montana State University, Bozeman, Montana

Extract

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Biofilms are communities of microbial cells and extracellular polymeric substances (EPS) attached to a surface. Bacteria exist preferentially in the biofilm state in nature and in many engineered systems. In this state, microbes tolerate antibiotics and disinfectants. Bacterial biofilms are now implicated in a wide range of human diseases and infections including cystic fibrosis, otitis media, chronic wounds, artificial joint and prosthesis infection, and many nosocomial infections. Biofilm-related infections and industrial fouling problems cost billions of dollars each year.

Type
Research Article
Copyright
Copyright © Microscopy Society of America 2008

References

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