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Correlative Electron Tomography and Elemental Microanalysis in Biology: A Preview

Published online by Cambridge University Press:  14 March 2018

Michael Marko ,
Terence Wagenknecht  and
Carmen Mannella
Michael Marko*
Affiliation:
Resource for Visualization of Biological Complexity, Wadsworth Center
Terence Wagenknecht
Affiliation:
Resource for Visualization of Biological Complexity, Wadsworth Center
Carmen Mannella
Affiliation:
Resource for Visualization of Biological Complexity, Wadsworth Center
*
marko@wadsworth.org

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The combination of electron tomography (three-dimensional reconstruction of an individual object from a series of EM tilt images) and elemental mapping (based on element-specific differences in interaction between the primary electron beam and the specimen) is at the very beginning of its application. This article reviews the first published results and considers some requirements and potential uses in biology, employing two examples from our own exploratory work.

Type
Research Article
Information
Microscopy Today , Volume 11 , Issue 6 , December 2003 , pp. 14 - 21
Copyright
Copyright © Microscopy Society of America 2003

References

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