Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-27T09:24:48.298Z Has data issue: false hasContentIssue false

Single Cell Force Measurements and Cell Adhesion

Published online by Cambridge University Press:  14 March 2018

Torsten Mueller*
Affiliation:
JPK Instruments AG, Berlin Germany
Tanja Neumann
Affiliation:
JPK Instruments AG, Berlin Germany

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

This short review describes the relevance of cell adhesion in cell biology. Starting with a short overview of the force range of adhesion related biological events and the current biophysical techniques for investigating these events, it will conclude with a description of the use of single cell force spectroscopy for quantifying mechanical properties such as stiffness, surface tension, and bond disruption forces.

Type
Research Article
Copyright
Copyright © Microscopy Society of America 2008

References

[1] Engler, A. et al.: Cell 126, 677-689 (2006)CrossRefGoogle ScholarPubMed
[2] Toh, Y.C. et al.: Nanotoday 1/3, 34-43 (2006)CrossRefGoogle Scholar
[3] Girard, P. et al.: Soft Matter 3, 307-326 (2007)CrossRefGoogle Scholar
[4] van Fliet, KJ. et al.: Acta Materialia 51, 5881-5905 (2003)CrossRefGoogle Scholar
[5] Robert, P. et al.: J. Mol. Recognit. 20, 432-447 (2007)CrossRefGoogle Scholar
[6] Krieg, M. et al.: Nature Cell Biology 10, 429-436 (2008)CrossRefGoogle Scholar