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Published online by Cambridge University Press: 14 March 2018
We are always trying to extend our vision through the four senses of sight, sound, touch and smeil. The microscopy devised by Hooke and Van Leeuwenhoek more than three centuries ago are examples of methods used to extend our visible vision, in fact, instrument designers since then have constructed microscopes using each one of our senses to give us peeks into the microworid. When Robert Hooke took some scrapings from his teeth and viewed the bacteria in these scrapings in his primitive microscope,1 a whole new view of the world ensued. It would, however, have been difficult to predict how microscopy would evolve in the following centuries.