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Using a Microscope to Measure the Glue that Holds us Together

Published online by Cambridge University Press:  14 March 2018

Stephen W. Carmichael
Stephen W. Carmichael*
Affiliation:
Mayo Clinic

Extract

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We think that adhesion molecules hold cells together. This is the "glue" that holds us, and every other multicellular life form on this planet, together. Intriguingly, the atomic force microscope has recently been used to directly measure the binding force of one of these adhesion molecules. We now have direct evidence that adhesion molecules have the physical properties required to hold cells together. This essential new information shows that these molecules can perform the function that have been assigned to them. You'll be delighted to know that this molecule is more than strong enough to do its job!

Type
Research Article
Information
Microscopy Today , Volume 3 , Issue 3 , April 1995 , pp. 6 - 7
Copyright
Copyright © Microscopy Society of America 1995

References

2 Carmichael, S.W., Microscopy isn't just for microscopists, anymore. Microscopy Today 94-5:24, 1994 Google Scholar

3 Dammer, U., Popescu, O., Wagner, P., Anselmetti, D., Gunlherodt, H.-J, and Misevic, G.N., Binding strength between cell adhesion proleoglycans measured by atomic farce microscopy, Science 267:1173–1175, 1995 Google Scholar.