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The duration of residual immunity following spontaneous cure of Plasmodium berghei in rats

Published online by Cambridge University Press:  06 April 2009

C. C. Draper
C. C. Draper
Affiliation:
Ross Institute of Tropical Hygiene, London School of Hygiene and Tropical Medicine
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Extract

1. In intact rats infected with P. berghei spontaneous eradication of infection has occurred by about 4 months after the day of inoculation.

2. These recovered rats show a strong residual immunity to reinfection with a heterologous strain, but this has begun to wane by 15–18 months after cure of the initial infection.

I owe many thanks to Miss W. J. Wall and Miss J. Wrugh of the Ross Institute for maintenance of the rats and assistance with the blood films.

Type
Research Article
Information
Parasitology , Volume 44 , Issue 3-4 , November 1954 , pp. 338 - 341
Copyright
Copyright © Cambridge University Press 1954

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References

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