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Neurobiology of parasitic platyhelminths: possible solutions to the problems of correlating structure with function

Published online by Cambridge University Press:  06 April 2009

R. A. Pax  and
J. L. Bennett
R. A. Pax
Affiliation:
Departments of Pharmacology and Toxicology and Zoology, Michigan State University, East Lansing, MI 48824, USA
J. L. Bennett
Affiliation:
Departments of Pharmacology and Toxicology and Zoology, Michigan State University, East Lansing, MI 48824, USA
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Extract

This paper provides an overview of research on the nervous system of parasitic platyhelminths. We have emphasized studies concerned with the physiological, pharmacological and biochemical nature of the major small molecule neurotransmitters of these parasites. We have attempted to provide a critical review of the work by focusing on important unresolved issues. Finally, we have focused on some recent work in our laboratory, using patch-clamp recording techniques and quantitative fluorescence cytometry, as an example of newer methods that will hopefully resolve some of the unanswered questions concerning the nervous system of these parasites.

Keywords

trematodescestodesplatyhelminthsneurotransmittersneurobiologyreceptorsion channels and second messengers.
Type
Research Article
Information
Parasitology , Volume 102 , supplement S1: Symposia of the British Society for Parasitology Volume 28:Parasite neurobiology , January 1991 , pp. S31 - S39
Copyright
Copyright © Cambridge University Press 1991

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