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Observations on the use of Trichostrongylus colubriformis (Nematoda) infections of guinea-pigs for laboratory experiments*

Published online by Cambridge University Press:  06 April 2009

R. F. Sturrock
R. F. Sturrock
Affiliation:
Research Scholar of the Animal Health Trust, Imperial College Field Station, Sunninghill, Berks.†
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Extract

Four groups of guinea-pigs were infected with a range of doses of T. colubriformis. The infections were followed by egg counts and weight measurements, and the adult worms were recovered from the animals post mortem. A multivariate analysis, details of which are given in an appendix, showed that the sensitivity of the measures used was, in descending order, final weight, total egg count and worm burden. The course of the infection is discussed in view of the apparent self-cure mechanism. Precautions are outlined for the experimental use of this hostparasite relationship.

The author is grateful to Professor B. G. Peters for his advice on this work, to Dr P. Silverman of Allen and Hanburys Limited for a supply of T. colubriformis infective larvae and to Dr R. E. Blackith for his advice on the statistical treatment of the data.

Type
Research Article
Information
Parasitology , Volume 53 , Issue 1-2 , May 1963 , pp. 189 - 199
Copyright
Copyright © Cambridge University Press 1963

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References

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