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The effect of colostrum on pigs pre-natally or post-natally exposed to Schistosoma japonicum

Published online by Cambridge University Press:  05 October 2004

M. E. TECHAU ,
M. V. JOHANSEN ,
P. LIND  and
N. ORNBJERG
M. E. TECHAU
Affiliation:
Danish Bilharziasis Laboratory, Jaegersborg Allé 1D, DK-2920 Charlottenlund, Denmark Danish Centre for Experimental Parasitology, Dyrlaegevej 100, 1870 Frederiksberg C, Denmark
M. V. JOHANSEN
Affiliation:
Danish Bilharziasis Laboratory, Jaegersborg Allé 1D, DK-2920 Charlottenlund, Denmark
P. LIND
Affiliation:
Department of Immunology and Biochemistry, Danish Veterinary Institute 27 Bülowsvej, DK-1790 Copenhagen V, Denmark
N. ORNBJERG
Affiliation:
Danish Bilharziasis Laboratory, Jaegersborg Allé 1D, DK-2920 Charlottenlund, Denmark
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Abstract

Pre-natal infection of Schistosoma japonicum in pigs may prove to be a useful model in shedding light on human pre-natal schistosomiasis. This study describes the effects of immune colostrum on worm burdens, tissue egg counts, liver pathology and crude worm or egg antigen-specific IgG and IgA responses, in groups of pigs pre-natally, pre-natally+post-natally or post-natally exposed to S. japonicum. Results suggest that pre-natal exposure and immune colostrum did not affect the establishment of a post-natal challenge infection. However, immune colostrum seemed to increase the levels of septal fibrosis in pre-natally exposed pigs. These findings indicate that further investigations will prove valuable, elucidating the influence of the parasitological and immunological status of the sow, on pre-natally exposed pigs, and on the ability of these pigs to develop resistance against S. japonicum later in life.

Keywords

Schistosoma japonicumpre-natal exposurecolostrumIgGIgA
Type
Research Article
Information
Parasitology , Volume 129 , Issue 5 , November 2004 , pp. 597 - 604
Copyright
© 2004 Cambridge University Press

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References

REFERENCES

ALLEN, J. E. & MAIZELS, R. M. ( 1996). Immunology of human helminth infection. International Archives of Allergy and Immunology 109, 3–10.CrossRefGoogle Scholar
BOGH, H. O., WILLINGHAM, A. L., JOHANSEN, M. V., ERIKSEN, L. & CHRISTENSEN, N. O. ( 1997). Recovery of Schistosoma japonicum from experimentally infected pigs by perfusion of liver and mesenteric veins. Acta Veterinaria Scandinavica 38, 147–155.Google Scholar
BUTTERWORTH, A. E. ( 1993). Immunology of schistosomiasis. In Human Schistosomiasis ( ed. Jordan, P., Webbe, G. & Sturrock, R. F.), pp. 331–336. CAB International, Wallingford.
CORT, W. W. ( 1921). Prenatal infestation with parasitic worms. Journal of the American Medical Association 76, 170–171.Google Scholar
EL TEMSAHI, M. M. & EL GOHARI, S. H. ( 1999). The possibility of transplacental transmission of experimental schistosomiasis. Journal of the Egyptian Society of Parasitology 29, 599–608.Google Scholar
ELOI-SANTOS, S. M., NOVATO-SILVA, E., MASELLI, V. M., GAZZINELLI, G., COLLEY, D. G. & CORREA-OLIVEIRA, R. ( 1989). Idiotypic sensitization in utero of children born to mothers with schistosomiasis or Chagas' disease. Journal of Clinical Investigation 84, 1028–1031.CrossRefGoogle Scholar
GIVER, H., JOHANSEN, M. V., CHRISTENSEN, N. O. & NANSEN, P. ( 1999). Schistosoma japonicum in the pig: a new technique for estimation of intestinal tissue egg counts. Southeast Asian Journal of Tropical Medicine and Public Health 30, 664–669.Google Scholar
HASSAN, M. M., HASSOUNAH, O. A., HEGAB, M., SALAH, K., EL MAHROUKY, L. & GALAL, N. ( 1997). Transmission of circulating schistosomal antigens from infected mothers to their newborns. Journal of the Egyptian Society of Parasitology 27, 773–780.Google Scholar
IBURG, T., BALEMBA, O. B., DANIZER, V., LEIFSSON, P. S. & JOHANSEN, M. V. ( 2002). Pathogenesis of congenital infection with Schistosoma japonicum in pigs. Journal of Parasitology 88, 1021–1024.CrossRefGoogle Scholar
JOHANSEN, M. V. ( 1998). Effect of praziquantel treatment on experimental porcine Schistosoma japonicum infection. Parasitology 116, 519–524.CrossRefGoogle Scholar
JOHANSEN, M. V., BOGH, H. O., NANSEN, P. & CHRISTENSEN, N. O. ( 2000). Schistosoma japonicum infection in the pig as a model for human schistosomiasis japonica. Acta Tropica 76, 85–99.CrossRefGoogle Scholar
JOHANSEN, M. V., IBURG, T., BOGH, H. O. & CHRISTENSEN, N. O. ( 2001). Postnatal challenge infections of congenitally Schistosoma japonicum-infected piglets. Journal of Parasitology 87, 813–815.Google Scholar
JOHANSEN, M. V. & ORNBJERG, N. ( 2004). Prenatal Schistosoma japonicum infection in piglets: effect of repeated exposure of the dams on treatment efficacy and susceptibility to challenge infections. Journal of Parasitology 90, 392–396.CrossRefGoogle Scholar
KIKUCHI, S. ( 1957). Studies on placental infection of Schistosoma japonicum. Sogo Igaku 14, 537–554.Google Scholar
KRESINA, T. F., CHEEVER, L. W., CHIREAU, M., JOHNSON, J., RAMIREZ, B., PETERS, P. & OLDS, G. R. ( 1992). Human EBV-transformed lymphocytes of patients with Schistosoma japonicum infection secrete idiotypically related immunoregulatory antibodies. Clinical Immunology and Immunopathology 65, 325–329.CrossRefGoogle Scholar
KRESINA, T. F. & OLDS, G. R. ( 1986). Concomitant cellular and humoral expression of a regulatory cross-reactive idiotype in acute Schistosoma japonicum infection. Infection and Immunity 53, 90–94.Google Scholar
LAMMIE, P. J., HITCH, W. L., WALKER ALLEN, E. M., HIGHTOWER, W. & EBERHARD, M. L. ( 1991). Maternal filarial infection as risk factor for infection in children. Lancet 337, 1005–1006.CrossRefGoogle Scholar
McGARVEY, S. T., ZHOU, X. N., WILLINGHAM, A. L., FENG, Z. & OLVEDA, R. ( 1999). The epidemiology and host-parasite relationships of Schistosoma japonicum in definitive hosts. Parasitology Today 15, 214–215.CrossRefGoogle Scholar
MOLONEY, N. A. & WEBBE, G. ( 1982). A rapid method for the infection of laboratory mice with Schistosoma japonicum. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 200–203.CrossRefGoogle Scholar
NARABAYASHI, H. ( 1914). Demonstration of specimens of Schistosoma japonicum: congenital infection and its route of infection (in Japanese). Kyoto Igaku Zasshi 11, 2–3.Google Scholar
NOUR, N. M., FAYED, M. A., HUSSEIN, S. M., SHAHEEN, H. I. & ABDEL-RAHEAM, R. S. ( 1990). Prevalence of morbidity of schistosomiasis among preschool children in Bani-Suef governorate. Journal of the Egyptian Society of Parasitology 20, 793–803.Google Scholar
PEDERSEN, I. T., JOHANSEN, M. V. & ORNBJERG, N. ( 2003). The effect of a low level primary Schistosoma japonicum infection on establishment of a challenge infection in pigs. Parasitology 127, 121–130.CrossRefGoogle Scholar
PHILLIPS, S. M., PERRIN, P. J., WALKER, D. J., FATHELBAB, N. G., LINETTE, G. P. & IDRIS, M. A. ( 1988). The regulation of resistance to Schistosoma mansoni by auto-anti-idiotypic immunity. Journal of Immunology 141, 1728–1733.Google Scholar
RIHET, P., DEMEURE, C. E., BOURGOIS, A., PRATA, A. & DESSEIN, A. J. ( 1991). Evidence for an association between human resistance to Schistosoma mansoni and high anti-larval IgE levels. European Journal of Immunology 21, 2679–2686.CrossRefGoogle Scholar
ROMIA, S. A., HANDOUSSA, A. E., YOUSEFF, S. A. & EL ZAYAT, M. M. ( 1992). Transplacental transfer of schistosomal antigens and antibodies. Journal of the Egyptian Society of Parasitology 22, 575–582.Google Scholar
ROSS, A. G., SLEIGH, A. C., LI, Y., DAVIS, G. M., WILLIAMS, G. M., JIANG, Z., FENG, Z. & McMANUS, D. P. ( 2001). Schistosomiasis in the People's Republic of China: prospects and challenges for the 21st century. Clinical Microbiology Reviews 14, 270–295.CrossRefGoogle Scholar
SHI, Y. E., JOHANSEN, M. V., LI, F. R., WILLINGHAM, A. L., BOGH, H. O., LIAO, L. G., HAN, J. J. & NING, C. X. ( 2001). An epidemiological investigation of congenital Schistosoma japonicum transmission in Hubei Province, PR China. Southeast Asian Journal of Tropical Medicine and Public Health 32, 323–325.Google Scholar
SMITHERS, R. S. & TERRY, R. J. ( 1967). Naturally acquired resistance to experimental infection of Schistosoma mansoni in the rhesus monkey (Macaca mulatta). Parasitology 55, 701–710.Google Scholar
SORENSEN, E., JOHANSEN, M. V., WILSON, S. & BOGH, H. O. ( 1999). Elucidation of Schistosoma japonicum population dynamics in pigs using PCR-based identification of individuals representing distinct cohorts. International Journal for Parasitology 29, 1907–1915.CrossRefGoogle Scholar
STEEL, C., GUINEA, A., McCARTHY, J. S. & OTTESEN, E. A. ( 1994). Long-term effect of prenatal exposure to maternal microfilaraemia on immune responsiveness to filarial parasite antigens. Lancet 343, 890–893.CrossRefGoogle Scholar
WANG, X. Y. ( 1959). Abortion in cattle (in Japanese). In Control of Domestic Animal Schistosomiasis, pp. 141–151. Ministry of Health, People's Republic of China (ed.). Shanghai Science and Technology Press, Shanghai, China.
WILLINGHAM, A. L., BOGH, H. O., JOHANSEN, M. V., CHRISTENSEN, N. O. & NANSEN, P. ( 1997). Schistosoma japonicum infection in the pig: the effect of a patent primary infection on a challenge infection. Acta Tropica 66, 51–59.CrossRefGoogle Scholar
WILLINGHAM, A. L., BOGH, H. O., VENNERVALD, B. J., JOHANSEN, M. V., ERIKSEN, L., CHRISTENSEN, N. O. & NANSEN, P. ( 1996). Worm establishment and egg production of Schistosoma japonicum in pigs infected by percutaneous methods or intramuscular injection. Veterinary Parasitology 61, 157–163.CrossRefGoogle Scholar
WILLINGHAM, A. L., JOHANSEN, M. V. & BARNES, E. H. ( 1998). A new technic for counting Schistosoma japonicum eggs in pig feces. Southeast Asian Journal of Tropical Medicine and Public Health 29, 128–130.Google Scholar
WILLINGHAM, A. L., JOHANSEN, M. V., BOGH, H. O., ITO, A., ANDREASSEN, J., LINDBERG, R., CHRISTENSEN, N. O. & NANSEN, P. ( 1999). Congenital transmission of Schistosoma japonicum in pigs. American Journal of Tropical Medicine and Hygiene 60, 311–312.CrossRefGoogle Scholar
WU, X. H., WANG, T. P., LU, D. B., HU, H. T., GAO, Z. B., ZHU, C. G., FANG, G. R., HE, Y. C., MEI, Q. J., WU, W. D., GE, J. H. & ZHENG, J. ( 2002). Studies of impact on physical fitness and working capacity of patients with advanced Schistosomiasis japonica in Susong County, Anhui Province. Acta Tropica 82, 247–252.CrossRefGoogle Scholar
ZHOU, X., MINGGANG, C., McMANUS, D. & BERGQUIST, R. ( 2002). Schistosomiasis control in the 21st century. Proceedings of the International Symposium on Schistosomiasis, Shanghai, 4–6 July 2001. Acta Tropica 82, 95–114.Google Scholar