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The effect of repeated chemotherapy on age-related predisposition to Ascaris lumbricoides and Trichuris trichiura

Published online by Cambridge University Press:  06 April 2009

L. Chan ,
S. P. Kan  and
D. A. P. Bundy
L. Chan
Affiliation:
Parasite Epidemiology Research Group, Department of Biology, Imperial College, London SW7 2BB, UK
S. P. Kan
Affiliation:
Department of Parasitology, Faculty of Medicine, University of Malaya, 59100 Kuala Lumpur, Malaysia
D. A. P. Bundy
Affiliation:
Parasite Epidemiology Research Group, Department of Biology, Imperial College, London SW7 2BB, UK
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Summary

This study examines the persistence of predisposition to Ascaris lumbricoides and Trichuris trichiura during repeated chemotherapy in an urban community in Kuala Lumpur, Malaysia. Significant predisposition was observed over 2 periods of reinfection with and without age-standardization of data. Analysis of different age groups indicated that predisposition was most strongly detectable in the younger age classes. The intensities of infection with both parasites were strongly correlated at each cycle of intervention, suggesting that individuals were similarly predisposed to both species.

Keywords

age-related predispositionAscarisTrichurischemotherapyMalaysia
Type
Research Article
Information
Parasitology , Volume 104 , Issue 2 , April 1992 , pp. 371 - 377
Copyright
Copyright © Cambridge University Press 1992

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