Published online by Cambridge University Press: 01 January 2022
We address Turkheimer’s argument that genome-wide association studies of behaviors and psychiatric traits will fail to produce coherent explanations. We distinguish two major sources of potential incoherence (heterogeneity and complexity), showing how they independently threaten coherence and considering how they are being and might better be addressed with protein and other databases and network tools.
Thanks to Niklas Andersson, Lindley Darden, Susan Fitzpatrick, Mark Povich, and two anonymous referees for comments and to Frederick Eberhardt especially for discussing s-t cuts. This project is funded in part by the John Templeton Foundation via a Genetics and Human Agency Award. This work is solely the responsibility of its authors and does not necessarily represent the official view of the funder.