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Depressive Illness, Pulse Rate and Forearm Blood Flow

Published online by Cambridge University Press:  29 January 2018

Peter Noble
Affiliation:
Institute of Psychiatry, Denmark Hill, London, S.E.5
Malcolm H. Lader
Affiliation:
Institute of Psychiatry, Denmark Hill, London, S.E.5

Extract

In depression alteration in mood is accompanied by pronounced physical and behavioural changes. Characteristically there is a decline in appetite, weight and libido, insomnia and a disturbance of diurnal rhythm. A slowing of thought and movement to the point of severe retardation or even stupor may occur. Anxiety is often present and in agitated depression is accompanied by restless psychomotor activity. As lesions in the hypothalamus may produce disturbances in appetite, weight, libido and sleep, it has been suggested that hypothalamic dysfunction may play a part in the aetiology of those depressions in which physical symptoms predominate (Pollitt, 1965).

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists, 1971 

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References

Barcroft, H., and Swan, H. J. C. (1953). Sympathetic Control of Human Blood Vessels. London.Google Scholar
Barcroft, H., Brod, J., Hejl, Z., Hirsjärvt, E. A., and Kitchin, A. H. (1960). ‘The mechanism of the vasodilatation in the forearm muscle during stress.’ Clinical Science, 19, 577–86.Google Scholar
Blair, D. A., Glover, W. E., Greenfield, A. D. M., and Roddie, I. C. (1959). ‘Excitation of cholinergic vasodilator nerves to human skeletal muscles during emotional stress.’ Journal of Physiology, 148, 633–47.Google Scholar
Board, F., Wadeson, R., and Persky, H. (1957). ‘Depressive affect and endocrine functions.’ Archives of Neurology and Psychiatry, 78, 612–20.Google Scholar
Carroll, B. J. (1969). ‘Hypothalamic-pituitary function in depressive illness: insensitivity to hypoglycaemia.’ British Medical Journal, iii, 27–8.Google Scholar
Carroll, B. J., Martin, F. I. R., and Davies, B. (1968). ‘Resistance to suppression by dexamethasone of plasma 11-OHCS levels in severe depressive illness.’ British Medical Journal, iii, 285–7.Google Scholar
Doig, R. J., Mummery, R. V., Wills, M. R., and Elkes, A. (1966). ‘Plasma Cortisol levels in depression.’ British Journal of Psychiatry, 112, 1263–7.Google Scholar
Ganong, W. F. (1969). Review of Medical Physiology. California.Google Scholar
Hamilton, M. (1960). ‘A rating scale for depression.’ Journal of Neurology, Neurosurgery and Psychiatry, 23, 5662.Google Scholar
Kelly, D. H. W. (1967). ‘The technique of forearm plethysmography for assessing anxiety.’ Journal of Psychosomatic Research, 10, 373–82.Google Scholar
Kelly, D. H. W., and Walter, C. J. S. (1969). ‘A clinical and physiological relationship between anxiety and depression.’ British Journal of Psychiatry, 115, 401–6.CrossRefGoogle ScholarPubMed
Lader, M. H., and Wing, L. (1969). ‘Physiological measures in agitated and retarded depressed patients.’ Journal of Psychiatric Research, 7, 89100.Google Scholar
Noble, P. J., and Lader, M. H. (1971). ‘Salivation and depressive illness, a psychometric and physiological study.’ Psychological Medicine, in press.Google Scholar
Palmai, G., Blackwell, B., Maxwell, A. E., and Morgenstern, F. (1967). ‘Patterns of salivary flow in depressive illness and during treatment.’ British Journal of Psychiatry, 113, 1297–308.Google Scholar
Pollitt, J. D. (1965). ‘Suggestions for a physiological classification of depression.’ British Journal of Psychiatry, 111, 489–95.Google Scholar
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