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The Effect of Urinary Fractions from Schizophrenic Patients on the Electrical Activity of the Brain

Published online by Cambridge University Press:  29 January 2018

D. Kemali
D. Kemali*
Affiliation:
Neuropsychiatric Research Unit, Medical Research Council, Carshalton, Surrey, and National Institute for Medical Research, Mill Hill, London
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Extract

In 1957 Professor Buscaino and the author reported the effect of intraperitoneal injection in mice of material from schizophrenic patients (1). The material was obtained from urine by treatment with activated charcoal and elution (2). These results have recently been confirmed by Fujita and Ging (3) who also found a characteristic toxic action of material from schizophrenic patients. Further work (4) showed that direct application to the cerebral cortex of the unanaesthetized rabbit of urinary material from schizophrenics caused the appearance of regular high voltage waves. The material obtained from the urine of controls, when applied to the cortex in the same concentration, did not have the same effect (5).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 110 , Issue 467 , July 1964 , pp. 576 - 581
Copyright
Copyright © Royal College of Psychiatrists, 1964 

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References

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