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Mixed Affective States and the Natural History of Manic-Depressive Psychosis

Published online by Cambridge University Press:  29 January 2018

C. M. H. Nunn*
Affiliation:
Professorial Unit, Knowle Hospital, Fareham, Hants, PO17 5NA

Summary

Since neither the unipolar nor the bipolar theories of manic-depressive psychosis explain all its features, an alternative model was tested. The hypotheses are that mixed affective psychoses represent a superimposition on hypomania of a second type of depression which can sometimes develop from the depressive phase of manic-depressive psychosis, and that schizophrenia occurring in the course of a manic-depressive illness is an alternative to mixed affective psychosis.

From an examination of the clinical histories of a random sample of people with bipolar manic-depressive psychosis, evidence was found to support both ideas.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1979 

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References

Bunney, W. F., Murphy, D. L. & Goodwin, F. K. (1972) The switch process in manic-depressive illness. Archives of General Psychiatry, 27, 295317.CrossRefGoogle ScholarPubMed
Coppen, A., Shaw, D. M., Malleson, A. & Costain, R. (1966) Mineral metabolism in mania. British Medical Journal, i, 71–5.Google Scholar
Court, J. (1968) Manic-depressive psychosis: an alternative conceptual model. British Journal of Psychiatry, 114, 1523–30.CrossRefGoogle ScholarPubMed
Hemsley, D. R. & Philips, M. C. (1975) Models of mania: an individual case study. British Journal of Psychiatry, 127, 7885.CrossRefGoogle ScholarPubMed
Himmelhoch, J. M., Mulla, D., Neil, J. F., Detie, T. P. & Kupfer, D. J. (1976) Incidence and significance of mixed affective states in a bipolar population. Archives of General Psychiatry, 33, 1062–6.CrossRefGoogle Scholar
Lewis, N. & Piotrowski, Z. (1954) Clinical diagnosis of manic-depressive psychosis. In Depression (eds. Hoch, P. M. and Zubin, J.). New York: Grune and Stratton.Google Scholar
Loudon, J. B., Blackburn, I. M. & Ashworth, C. M. (1977) A study of the symptomatology and course of manic illness using a new scale. Psychological Medicine, 7, 723–9.CrossRefGoogle ScholarPubMed
Nunn, C. M. H. (1978) A Model of the Functional Psychoses. Book in preparation.Google Scholar
Tsuang, M. T., Dempsey, M. & Rausher, F. (1976) A study of atypical schizophrenia. Archives of General Psychiatry, 33, 1157–60.CrossRefGoogle ScholarPubMed
Sheldrick, C., Jablensky, A., Sartorius, N. & Shepherd, M. (1977) Schizophrenia succeeded by affective illness: catamnestic study and statistical enquiry. Psychological Medicine, 7, 619–24.CrossRefGoogle ScholarPubMed
Winokur, G., Clayton, P. L. & Reich, T. (1969) Manic-Depressive Illness. The C. V. Mosby Company, St. Louis.Google Scholar
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