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The Nyctohemeral Rhythm of Plasma Cortisol in Mental Illness in Nigerians
Published online by Cambridge University Press: 29 January 2018
Extract
Reports on adrenocortical function in mental illness have been conflicting, and there has been a failure to replicate results, especially with plasma Cortisol measurements (Gibbons, 1968; Segraves, 1970; and Franzen, 1971). Also, the study of particular diagnostic categories of patients appears to introduce a sampling bias, whilst isolated measurements usually fail to assess hypothalamo-pituitaryadrenal function. We have therefore undertaken a blind assessment study of the nyctohemeral rhythm of plasma Cortisol in Nigerian inmates of the Aro Neuropsychiatric Hospital and Lantoro Institution in Abeokuta, which operate respectively as open and closed treatment centres (Asuni, 1967).
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- Copyright © Royal College of Psychiatrists, 1973
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