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Orphenadrine

Published online by Cambridge University Press:  02 January 2018

Lars Slørdal
Affiliation:
Department of Pharmacology and Toxicology, Norwegian University of Science and Technology, N–7005 Trondheim, Norway
Pål Gjerden
Affiliation:
Department of Psychiatry, Telemark Central Hospital, N–3710 Skien, Norway
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Abstract

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Copyright
Copyright © 1999 The Royal College of Psychiatrists 

References

Blomquist, M., Bonnichsen, R. & Schubert, B. (1971) Lethal orphenadrine intoxications. A report of five cases. Zeitschrift für Rechtsmedizin, 68, 111.Google Scholar
Bosche, J. & Mallach, H. J. (1969) Uber anatomische und chemisch toxikologische Befunde bei einer todlichen Vergiftung durch Orphenadrin. Archiv Toxikologie, 25, 7682.Google Scholar
Bozza-Marubini, M., Frigerio, A., Ghezzi, R., et al (1977) Two cases of severe orphenadrine poisoning with atypical features. Acta Pharmacologica & Toxicologica, 41, 137152.Google Scholar
Buckley, N. & McManus, P. (1998) Fatal toxicity of drugs used in the treatment of psychotic illnesses. British Journal of Psychiatry, 172, 461464.Google Scholar
Catterson, M. L. & Martin, R. L. (1994) Anticholinergic toxity masquerading as neuroleptic malignant syndrome: a case report and review. Annals of Clinical Psychiatry, 4, 267269.Google Scholar
Chang, T. K., Weber, G. F., Crespi, C. L., et al (1993) Differential activation of cyclophosphamide and iphosphamide by cytochrome P-450 2B and 3A in human liver microsomes. Cancer Research, 53, 56295637.Google Scholar
Clarke, B., Mair, J. & Rudolf, M. (1985) Acute poisoning with orphenadrine. Lancet, i, 1386.CrossRefGoogle Scholar
Cresteil, A., Monsarrat, B., Alvinerie, P., et al (1994) Taxol metabolism by human liver microsomes: identification of cytochrome P450 isoenzymes involved in its biotransformation. Cancer Research, 54, 386392.Google Scholar
Deceuninck, F., Silverman, R. M. & Veltman, J. G. J. (1973) Een patiente met een psychose na intoxicatie met orfenadrin. Nederlands Tijdschrift voor Geneeskünde, 117, 2527.Google Scholar
Dollery, C., (ed.) (1991) Therapeutic Drugs, Vol. 1. London: Churchill Livingstone.Google Scholar
Ellenhorn, M. J. (1997) Medical Toxicology. Diagnosis and Treatment of Human Poisoning. Baltimore, MD: Williams & Wilkins.Google Scholar
Gjerden, P., Engelstad, K. S., Pettersen, G., et al (1998) D⊘dsfall forårsket av antikolinerge antiparkinson-medikamenter. Et nasjonalt 11-årsmateriale. Tidsskrift for den Norske Lægeforening, 118, 4244.Google Scholar
Hewer, W. & Biedert, S. (1988) Delirantes syndrom bei biperiden-intoxikation. Fortschritte der Neurologie-Psychiatrie, 56, 133136.CrossRefGoogle Scholar
Labout, J. J. M., Thijssen, C. T., Keijser, G. G. J., et al (1982) Difference between single and multiple dose pharmacokinetics of orphenadrine hydrochloride in man. European Journal of Clinical Pharmacology, 21, 343350.CrossRefGoogle ScholarPubMed
Millar, W. M. (1977) Deaths after overdoses of orphenadrine. Lancet, ii, 566.CrossRefGoogle Scholar
Robinson, A. E., Holder, A. T., McDowall, R. D., et al (1977) Forensic toxicology of some orphenadrine-related deaths. Forensic Science, 9, 5362.Google Scholar
Sangster, B., van Heijst, A. N. P. & Zimmerman, A. N. E. (1978) Vergifting door orfenadrine. Nederlands Tijdschrifi voor Geneeskünde, 122, 988992.Google Scholar
Särnquist, F. & Larson, C. P. (1973) Drug-induced heat stroke. Anesthesiology, 3, 348350.CrossRefGoogle Scholar
del Villar, G. & Liddy, M. (1976) Two deaths involving benztropine. Bulletin of the International Association of Forensic Toxicologists, 12, 1112.Google Scholar
Wade, L. C. & Ellenor, G. L. (1980) Combination of mesoridazine and benztropin mesylate induced paralytic ileus. Two case reports. Drug Intelligence and Clinical Pharmacy, 14, 1722.CrossRefGoogle Scholar
Wilkinson, L. G., Thomson, B. M. & Pannell, L. K. (1983) A report on the analysis of orphenadrine in post mortem specimens. Journal of Analytical Toxicology, 7, 7275.Google Scholar
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