Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-14T16:54:19.313Z Has data issue: false hasContentIssue false

Sodium Valproate as an Antidepressant

Published online by Cambridge University Press:  02 January 2018

L. I. Kemp*
Affiliation:
Mid-Kent Rotational Training Scheme in Psychiatry, Maidstone Hospital, Barming, Maidstone, Kent ME16 9QQ

Abstract

A patient with chronic depression responded to treatment for her major depressive episodes, but was left with a dysthymia which was eventually relieved by anticonvulsants. Sodium valproate may be of use in a range of affective disorders.

Type
Brief Reports
Copyright
Copyright © The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R). Washington, DC: APA.Google Scholar
Calabrese, J. R. & Delucchi, G. A. (1990) Spectrum of efficacy of valproate in 55 patients with rapid-cycling affective disorder. American Journal of Psychiatry, 147, 431434.Google Scholar
Cassano, G. B., Maggini, C. & Akiskal, H. (1983) Short-term, subchronic and chronic sequelae of affective disorders. Psychiatric Clinics of North America, 6, 5558.Google Scholar
Emrich, H. M., Dose, M. & Von Zerssen, D. (1985) The use of sodium valproate, carbamazepine and oxcabazine in patients with affective disorders. Journal of Affective Disorders, 8, 243250.Google Scholar
Jann, M. W., Garrelts, J. C., Ereshefshy, L., et al (1984) Alternative drug therapies for mania: a literature review. Drug Intelligence and Clinical Pharmacy, 18, 577589.CrossRefGoogle ScholarPubMed
Klosiewicz, L. (1985) The prophylactic influence of valproic acid amide in affective illness. Psychiatria Polska (Warsaw), 19, 2329.Google Scholar
Kubanek, J. L. & Rowell, R. C. (1946) The use of dilantin in the treatment of psychotic patients unresponsive to other treatment. Diseases of the Nervous System, 7, 14.Google Scholar
Lambert, P. A., Carraz, G., Borselli, S., et al (1966) Action neuropsychotrope d'un nouvel antiepileptique; le Depamide. Annates Medico-psychologiques (Paris), 1, 707710.Google Scholar
McElroy, S. L., Keck, P. E., Pope, H. G., et al (1988) Valproate in the treatment of rapidly cycling bipolar disorder. Journal of Clinical Psychopharmacology, 8, 275279.Google Scholar
Pope, H. G., McElroy, S., Satlin, A., et al (1988) Head injury, bipolar disorder and response to valproate. Comprehensive Psychiatry, 29, 3438.Google Scholar
Post, R. M. & Uhde, T. W. (1983) Treatment of mood disorders with antiepileptic medications; clinical and theoretical implications. Epilepsia, 24 (suppl. 2), 97108.Google Scholar
Scott, J. (1988) Chronic depression. British Journal of Psychiatry, 153, 287297.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.