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Urinary Excretion of some Purine Bases in Normal and Schizophrenic Subjects

Published online by Cambridge University Press:  29 January 2018

D. A. Booth
Affiliation:
Biochemistry Department, Institute of Psychiatry, University of London, Maudsley Hospital, London, S.E.5
E. B. O. Smith
Affiliation:
Herrison Hospital, Dorchester, Dorset

Extract

Kishimoto (1958) reported quantitative and qualitative peculiarities in the absorption spectra of body fluids in schizophrenia, and considered that there were abnormalities in the oxidation of adenine through hypoxanthine and xanthine to uric acid.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1964 

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References

Bollard, B. M., Culpan, R. H., Marks, N., McIlwain, H., and Shepherd, M. (1960). “Purines in the urine of normal and schizophrenic subjects.” J. Ment. Sci., 106, 1250.Google Scholar
Cavalieri, L. F., Fox, J. J., Stone, A., and Chang, N. (1954). “On the nature of xanthine and substituted xanthines in solution.” J. Amer. Chem. Soc., 76, 1119.Google Scholar
Cornish, H. H. (1956). “The Metabolism of Theobromine, Theophylline and Caffeine” (Ph.D., 1956, University of Michigan). Univ. Microfilms 21165. Ann Arbor, Michigan.Google Scholar
Cornish, H. H. and Christman, A. A. (1957). “A study of the metabolism of theobromine, theophylline and caffeine in man.” J. biol. Chem., 228, 315.CrossRefGoogle Scholar
Kalckar, H. M. (1947). “Differential spectrophotometry of purine compounds by means of specific enzymes.” Ibid., 167, 429.Google Scholar
Kishimoto, K. (1958). “Disturbance of purine metabolism in schizophrenia” Confin. neurol., 18, 242.Google Scholar
Weissman, B., Bromberg, P. A., and Gutman, A. B. (1957). “The purine bases of human urine.” J. biol. Chem., 224, 407, 423.CrossRefGoogle Scholar
Weissman, B., Bromberg, P. A., and Gutman, A. B. and Gutman, A. B. (1957). “The identification of 6-succinoaminopurine and of 8-hydroxy-7-methyl-guanine as normal human urinary constituents.” Ibid., 229, 239.Google Scholar
Williams, J. N. (1950). “A micromethod for the determination of xanthine and guanine in urine.” Ibid., 184, 627.Google Scholar
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