A new suprabenthic mysid, Mysidopsis cachuchoensis sp. nov., is described from specimens sampled with a suprabenthic sled at the ‘Le Danois' Bank (the ‘El Cachucho' Marine Protected Area; southern Bay of Biscay). The main distinguishing features of this new species are the structure of its eyestalk and antennal scale as well as the armature of its telson and uropodal endopods. Inferred from the present unique record (828 m depth, inner basin between the bank and the Cantabrian shelf), it seems to be a rare endemic species of the bank, living on muddy bottoms of the upper bathyal.