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Focusing primarily on descriptive phenotypes for psychopathology, this chapter reviews the history and philosophy of operational definitions, emphasizing their provisional nature under the auspices of open concepts. It also reintroduces an important feature of operational definitions as originally proposed, namely the role of conventions in both defining and redefining the meaning of empirical concepts. It tentatively suggests that a shift toward a scientific realist conception of construct validation had the perhaps unintended consequence of obscuring the intrinsically provisional nature of concepts for psychological phenotypes. It explicates open concepts with the examples of schizophrenia, the five factor model of personality, and endophenotypes.
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