Both sublethal and lethal doses of fenitrothion treatment caused positive temperature toxicity relationship in three lepidopteran fifth instar larvae, Achaea Janata, Mythimna separata and Bombyx mori.
The LD50 value was very low at 30°C compared to 28 and 18°C. In all the three species, the insecticide caused greater rate of regurgitation of body fluid at higher temperature. It is believed that the loss of body fluid causes desiccation and enhances the poisoning effects of fenitrothion.