Two conventional greenhouses were modified into a containment facility for the study of foreign noxious weed species that could be dangerous to North American agriculture. The facility was designed for research on the biology, ecology, and weed control technology of foreign noxious weeds, without the escape of propagules. Two growth chambers and a germinator are located within the containment facility for evaluations under controlled environmental conditions. A standard operating procedure is followed to preclude the escape of weed seeds or propagules while minimizing restrictions to research. The facilities are locked and located in a secure fenced area to reduce the probability of accidental or intentional damage. Procedures for emergencies have been designed to facilitate aid without compromising the containment security. Knowledge concerning weeds that have the potential to threaten North American agriculture will be gained from research performed within this facility.