During the late sixteenth and early seventeenth centuries—the height of European demonological interest—England experienced a series of demonic possession cases that gained substantial attention from the clergy and laypeople alike. Reported across sensationalist pamphlets and learned demonological treatises, these cases were presented as extraordinary tokens of God's providence intended to be interpreted and responded to by those involved. English Calvinists during this period were largely interested in demonic possession for three primary reasons: what providential meaning this spiritual affliction offered, what action God was compelling them to carry out, and, more importantly, what profit they could gain in fulfilling their godly duties. The profit cited by these Calvinists was a glimpse into their predestined fate. This article argues that demonic affliction was fashioned as an emblematic phenomenon by English Calvinist communities with dispossession (exorcism) cast as a definitive form of spiritual warfare designed to provide comfort for the faithful and guide them toward a blessed conclusion. In this context, possession functioned as a providential catalyst: a call to carry out dispossession that, once fulfilled, brought the entire act to completion. Examining four possession textual accounts in detail, with a particular focus on the exploits of the controversial Puritan exorcist John Darrell, this article examines the intellectual construction of spirit possession and exorcism within an aligned Calvinist providential and eschatological framework. These cases exemplify many of the prevailing interpretations of spirit possession in the early modern English context and illustrate how this affliction offered individuals a potential salve to the vexed nature of Calvinist predestination.