The solar activity has been proposed as one of the main factors of Earth's climate variability, however biological processes have been also proposed. Dimethylsulfide (DMS) is the main biogenic sulfur compound in the atmosphere. DMS is mainly produced by the marine biosphere and plays an important role in the atmospheric sulfur cycle. Currently it is accepted that terrestrial biota not only adapts to environmental conditions but influences them through regulations of the chemical composition of the atmosphere. In the present study we used different methods of analysis to investigate the relationship between the DMS, Low Clouds, Ultraviolet Radiation A (UVA) and Sea Surface Temperature (SST) in the Southern Hemisphere. We found that the series analyzed have different periodicities which can be associated with climatic and solar phenomena such as El Niño, the Quasi-Biennial Oscillation (QBO) and the changes in solar activity. Also, we found an anticorrelation between DMS and UVA, the relation between DMS and clouds is mainly non-linear and there is a correlation between DMS and SST. Then, our results suggest a positive feedback interaction among DMS, solar radiation and cloud at time-scales shorter than the solar cycle.