Field studies were conducted in 2009 and 2010 on established commercial cranberry farms in southeastern Massachusetts to evaluate cranberry vine injury and yield with two rates of dichlobenil (1.8 and 2.7 kg ai ha−1) applied at various growth stages starting in mid-May. Four varieties were evaluated: ‘Ben Lear', ‘Early Black', ‘Howes', and ‘Stevens'. Ben Lear vines exhibited leaf-stress symptoms in both years, and Howes and Stevens vines had leaf symptoms in 1 yr. Data indicated that applications made during periods of flower-part development and growth (jewel through bloom) had the highest injury ratings. Growth stage affected injury ratings by variety and dichlobenil rate in 1 out of 2 yr. In all cases, leaf symptoms abated by the end of the season. No effect on yield (wt of fruit per unit area) was detected for any treatment combination on any variety in either year. Data from the present study support pursuit of future studies and can guide management decisions for dodder control to a limited extent. Longer studies are needed to fully evaluate repeated, annual applications of dichlobenil dispensed during periods of rapid growth on cranberry vine development and yield. Further work is also needed to document the practical use of delayed applications of dichlobenil for dodder management.