Mycobacterium tuberculosis is the cause of tuberculosis (TB), a granulomatous illness that mostly affects the lungs. Pakistan is one of the eight nations that accounts for two-thirds of all new cases of developing TB. TB has long been an endemic disease in Pakistan. According to the World Health Organization (WHO) estimates, the nation has over 500 000 incident TB infections per year, with a rising number of drug-resistant cases. Recently, the coexistence of COVID-19 and TB in Pakistan has provided doctors with a problem. Fever or chills, cough, shortness of breath or difficulty breathing are all signs of COVID-19. After SARS-CoV-2 infection, cough might persist for weeks or months and it is frequently accompanied by persistent tiredness, cognitive impairment, dyspnoea or pain – a group of long-term consequences known as post-COVID syndrome or protracted COVID. Coughing with mucus or blood, and coughing that continues over 2 months are indications of TB. The same clinical presentation features make it difficult for healthcare personnel to effectively evaluate the illness and prevent the spread of these fatal diseases. Pakistan lacks the necessary healthcare resources to tackle two contagious diseases at the same time. To counteract the sudden increase in TB cases, appropriate management and effective policies must be implemented. Thus, in order to prevent the spread of these infectious diseases, it is critical to recognise and address the problems that the healthcare sector faces, as well as to create an atmosphere in which the healthcare sector can function at its full potential.

This article focuses on the 1935 discovery of what is now believed to be a selenium deficiency disorder in the Japanese client state of Manchukuo. The epicenter of this disease had served as pasture for Oirat Mongols until the late nineteenth century. Opening up the land for reclamation by Chinese migrants put greater pressure on each acre to produce food. With a limited supply of selenium in the soil, the intake of this mineral by crops decreased over time, especially under the extractive conditions of the soybean industry during the Japanese occupation. Japanese theories on climate and hygiene made legible the consequences of transforming this nomadic borderland into an agrarian heartland on colonized bodies. By bringing attention to the understudied Mongol territories in Manchukuo, this essay goes beyond environmental histories bound by the nation-state to reveal the corporeal costs of settler colonialism and ecological imperialism.

In the UK, recent mean temperatures have consistently increased by between 1°C and 4°C compared to the 30-year monthly averages. Furthermore, all available predictive models for the UK indicate that the climate is likely to change further and feature more extreme weather events and a trend towards wetter, milder winters and hotter, drier summers. These changes will alter the prevalence of endemic diseases spatially and/or temporally and impact on animal health and welfare. Most notable among these endemic parasites are the helminths, which have been shown to be very strongly influenced by both the short-term weather and climate through effects on their free-living larval stages on pasture. In this review, we examine recent trends in prevalence and epidemiology of key helminth species and consider whether these could be climate-related. We identify likely effects of temperature and rainfall on the free-living stages and some key parasite traits likely to determine parasite abundance under changed climatic conditions. We find clear evidence that climate change, especially elevated temperature, has already changed the overall abundance, seasonality and spatial spread of endemic helminths in the UK. We explore some confounders and alternative explanations for the observed patterns. Finally, we explore the implications of these findings for policy makers and the livestock industry and make some recommendations for future research priorities.

In this paper we develop a model for describing the spread of the parasitic disease bilharziasis. The detailed model first developed (Model A) is made more tractable by replacing infecting population sizes by their expected values in the transition probabilities, giving Model B. Using this approximating model it is possible to examine the nature of the spread of the disease and the effects of control measures. The effects of a particular control measure are examined in order to compare Models A and B.