In the human body there are many joints whose functions are very similar to revolute joints. To avoid the complexity of these joints, they are usually substituted by revolute joints in many humanoid robots. Revolute joints have purely rotational motion along their fixed axis, while real joints in the human body have Instantaneous Rotational Axis (IRA) due to their configuration. Substitution of this kind of human joints with revolute (hinge) joints in robots changes the kinematics of joints. Knowing the exact characteristics of the moving axis of rotation in human joints is a prerequisite for the kinematic study of a joint. Here the main geometrical difference between these kinds of joints in humans and their simplified (hinge-like) models in robots is described. Then, as a case study, the mechanism of the three joints of the index finger are compared with their hinge-like model using a multi-body code to understand when revolute joints can be substituted for anthropometric joints in hand exoskeletons and robotic hands. Furthermore, the position of IRA and its distance from the center of the condyle of the joint are presented. The concept and the results can be extended for other fingers and all similar joints, and can be used in humanoid robots, hand exoskeletons and robotic hands.