The magnetorheological (MR) damper is a new device proposed for structural protection. It is filled with MR fluid that can be changed, when exposed to a magnetic field, regularly from free flowing liquid, linear viscous one to semi-solid. A phenomenological model based on the Bouc-Wen hysteresis model is adopted to predict both the force-displacement behavior and the complex nonlinear force-velocity response. The theory of fuzzy control is adopted here to determine the command voltage of MR dampers, but the applying of fuzzy control rules has always to deal with the classic problem of optimization. And due to the structural responses of analysis results, it can be confirmed that the reducing effects have an obviously improvement after an optimization by genetic algorithm.