A general exchangeable model is introduced to study gene survival in populations whose size changes without density dependence. Necessary and sufficient conditions for the occurrence of fixation (that is the proportion of one of the types tending to 1 with probability 1) are obtained. These are then applied to the Wright–Fisher model, the Moran model, and conditioned branching-process models. For the Wright–Fisher model it is shown that certain fixation is equivalent to certain extinction of one of the types, but that this is not the case for the Moran model.
