The province of Khurāsān constituted the centre of political, cultural, and religious life in the Sunni Islamic world from the ninth until the mid-twelfth century, after which Khurāsān was completely eclipsed. The question of how this occurred has remained almost completely unstudied; and the one study that there is does not consult the key primary literary sources for the time. The purpose of this article, therefore, is to re-examine what the primary sources reveal about the catastrophic cultural and political eclipse of Khurāsān in the mid-twelfth century, in order to demonstrate that this catastrophe was not due to “climate, cotton and camels” – in fact, Khurāsān was doing very well until the 1150s – but to concrete human agency and action: namely, the province's destruction by the rampaging Oghuz Turkmens after Sultan Sanjar had been taken captive by them in 1153, thus leading directly to the downfall of the Great Seljuq Sultanate.