Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

4 results

  • Infantile recurrent respiratory papillomatosis: review of adjuvant therapies

  • A Patel, N Orban
  • Journal:
    The Journal of Laryngology & Otology / Volume 135 / Issue 11 / November 2021
    Published online by Cambridge University Press:
    02 September 2021, pp. 958-963
    Print publication:
    November 2021
  • Background

    Recurrent respiratory papillomatosis is a potentially life-threatening condition characterised by the growth of exophytic lesions within the larynx and trachea. The principal aim of management is maintenance of an adequate airway by surgical debulking. Several adjuvant therapies have been used to varying effect to reduce the burden of this disease and increase the interval between debulking procedures. The most severe cases present in children aged under three years, who are therefore most likely to need adjuvant therapies. The current evidence base on adjuvant treatments relating to children who present aged under three years has been reviewed.

    Methods

    A literature review of articles in Cochrane, PubMed and Embase databases was carried out. Given the rarity of the condition in this age group, all the literature relates to case reports and case series.

    Results and conclusion

    The following adjuvant therapies have been used in children who presented under three years of age: quadrivalent human papilloma virus vaccine, intralesional cidofovir, pegylated interferon, alpha-interferon, cimetidine and cetuximab.

  • Treatment of paediatric laryngeal papillomas: web survey of British Association of Paediatric Otolaryngologists

  • J Manickavasagam, K Wu, N D Bateman
  • Journal:
    The Journal of Laryngology & Otology / Volume 127 / Issue 9 / September 2013
    Published online by Cambridge University Press:
    08 August 2013, pp. 917-921
    Print publication:
    September 2013
  • Background and objective:

    Recurrent respiratory papillomatosis is the most common benign neoplasm of the larynx in children. Intralesional injection of cidofovir may have some potential as an adjunctive treatment. There is no standardised protocol in the UK for the management of recurrent respiratory papillomatosis. This study aimed to investigate the management practices of surgeons treating paediatric recurrent respiratory papillomatosis in the UK.

    Method:

    A web questionnaire survey was sent by e-mail to all members of the British Association of Paediatric Otorhinolaryngology.

    Results:

    Out of 35 respondents, 23 were at that time treating children with recurrent respiratory papillomatosis. Nineteen respondents preferred to use a microdebrider, 12 preferred laser, and 5 preferred cold steel along with either laser or a microdebrider. Twelve surgeons used cidofovir for selected patients and 12 surgeons did not use cidofovir for any patients. Cidofovir was considered after 0–4 surgical procedures by seven respondents, after 4–6 surgical procedures by four respondents and after 6 surgical procedures by six respondents. Eleven respondents warned patients about the possible side effects of cidofovir and five gave no warning.

    Conclusion:

    There was no consensus as to when it would be appropriate to use cidofovir, indicating the need for cidofovir usage guidelines.

  • Chapter 16 - Anesthesia for head and neck flap reconstructive surgery

  • from Section 3 - Anesthesia for head and neck surgery
  • Edited by Basem Abdelmalak, John Doyle
  • Book:
    Anesthesia for Otolaryngologic Surgery
    Published online:
    05 November 2012
    Print publication:
    18 October 2012, pp 151-162

  • Summary

    This chapter discusses the minimal synopsis of selected airway pathology in terms of associated anesthetic and airway implications. The case types covered are those where awake intubation by some means is often the method of choice. Epiglottitis can occur in adults too but the situation is less dreadful because the adult airway is larger. Retropharyngeal abscess formation may occur from bacterial infection of the retropharyngeal space secondary to tonsillar or dental infections. Airway tumors can be benign or malignant, but regardless of type, suffocation from airway obstruction is always a potential concern. Nasal polyps and polyps elsewhere in the airway can lead to partial or complete airway obstruction. Patients with laryngeal papillomatosis caused by a HPV infection may require frequent application of laser treatment for attempted eradication of the papillomas. Since Ludwig's angina is often associated with trismus, nasal fiberoptic intubation is frequently needed.