This paper optimises two-ship collision-avoidance manoeuvres accounting for both collision risk and fuel use. A collision-avoidance manoeuvring optimisation model is developed to minimise fuel consumption while assuring ships' operational safety. The model can optimally determine when to begin collision-avoidance actions, how to change courses, and what rudder angles are needed. A quantitative scenario simulation is developed to illustrate the model application. The methodology can be further developed to guide practical ship collision-avoidance manoeuvring decisions made under more operational scenarios. In particular, this research can contribute to the development of computer-aided collision-avoidance operations to improve the safety and energy efficiency of maritime transportation.