The earliest peopling of South America remains a contentious issue. Despite the growing amount of new evidence becoming available, and improved excavation and dating techniques, few sites have yet to be securely assigned to a period earlier than 12000 BP. The Santa Elina shelter in Brazil, located at the convergence of two major river basins, is one of them. The excavations at the site, including the results of various dating programmes, are described here along with reflections on the unique insights offered by Santa Elina into early migration routes into the Southern Cone.