Subcomponents of the N200 component of the event-related
brain potential believed to be differentially sensitive
to involuntary and voluntary cognitive processes were examined.
Nonpatients (N = 131) identified initially by
the Chapman and Depue research scales and classified later
on the basis of diagnostic symptom clusters and family
psychiatric history provided converging evidence for an
intact mismatch negativity subcomponent. In contrast, the
N2b subcomponent distinguished several groups of subjects.
Results suggested abnormal voluntary cognitive processing,
perhaps reflecting compensatory efforts in subjects at
risk for or manifesting psychopathology, particularly those
showing negative symptoms.