Peripartum psychiatric disorders are common, and it is likely that an obstetric anaesthesiologist will be involved with the care of a patient with one of these disorders. The most common psychiatric disorders encountered in the peripartum period include depression, anxiety, bipolar disorder, post-traumatic stress disorder, and schizophrenia. These conditions are commonly underdiagnosed and undertreated but may have grave maternal and neonatal consequences. Additionally, postpartum psychiatric disorders, specifically anxiety and depression, are common complications of childbirth. The rising prevalence of these disorders in the peripartum period necessitates an understanding of the epidemiology, management, and treatment options. Evidence on how psychiatric disorders and their treatment can affect the mother, baby, and the delivery of anesthesia care is presented. This chapter reviews important anesthesia considerations for pregnant patients with psychiatric disorders and interactions that may occur between anesthesia and the medical management of these disorders. Additionally, interventions and prevention techniques to improve patient care and manage postpartum psychiatric sequelae are explored.