This article examines the effect of geographical proximity on targeting patterns during Ebola-era xenophobic outbursts by Senegalese against a migrant Peul population of Guinean origins. It highlights the limited extent to which epidemics shape the micro-dynamics of outbreaks of xenophobia during public health crises, demonstrating that epidemics are not defining events that inflect inter-group relations. They mostly reinforce long-persisting patterns of exclusion. The conclusion is that the contours of xenophobia in contexts marked by public health crises and in those situations in which these issues of public health do not constitute a major concern tend to mirror each other.