Burn-in is a procedure used for eliminating weak components in a mixed population. In this paper we focus on general mixed populations. Three types of results are established. First, it is shown that any mixed population displays a type of monotonicity property which is appropriate for burn-in. Second, it is shown that if, asymptotically, components have constant failure rates, then the mixed population will also asymptotically have a constant failure rate and this will correspond to the rate of the strongest subpopulation of the mixture. Finally, it is shown for a reasonable cost function, that if one mixture distribution dominates another in a strong sense, the resulting mixture of the dominant distribution will have larger optimal burn-in time.