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1 results

  • Head and neck sarcomas: clinical and histopathological presentation, treatment modalities, and outcomes

  • M Stavrakas, I Nixon, K Andi, R Oakley, J P Jeannon, A Lyons, M McGurk, T Guerrero Urbano, S Thavaraj, R Simo
  • Journal:
    The Journal of Laryngology & Otology / Volume 130 / Issue 9 / September 2016
    Published online by Cambridge University Press:
    01 August 2016, pp. 850-859
    Print publication:
    September 2016
  • Background:

    Sarcoma of the head and neck is a rare condition that poses significant challenges in management and often requires radical multimodality treatment.

    Objectives:

    This study aimed to analyse current clinical presentation, evaluation, management dilemmas and oncological outcomes.

    Methods:

    Computer records and case notes were analysed, and 39 patients were identified. Variables were compared using Pearson's chi-square test and the log-rank test, while survival outcomes were calculated using the Kaplan–Meier method.

    Results:

    The histopathological diagnosis was Kaposi sarcoma in 20.5 per cent of cases, chondrosarcoma in 15.3 per cent and osteosarcoma in 10.2 per cent. A range of other sarcomas were diagnosed in the remaining patients. The site of disease was most commonly sinonasal, followed by the oral cavity and larynx.

    Conclusion:

    Wide local excision with clear resection margins is essential to achieve local control and long-term survival. There is a need for cross-specialty collaboration in order to accrue the evidence which will be necessary to improve long-term outcomes.