Pale swallow-wort is a nonnative vine, invading natural areas across much of the northeastern United States and southeastern Canada. Control of this clump-forming herbaceous perennial has been difficult. We conducted a 2-yr study (2005–2006) in a heavily infested site in Chaumont, NY to assess the response of swallow-wort to triclopyr applied once as a foliar treatment (1.9 kg ae/ha) (2005 only) alone or in combination with clipping 4 wk later, followed by a single clipping in 2006. We also evaluated the response of swallow-wort to one or two clippings during each of the 2 yr. Two yr after treatments began, swallow-wort cover was lower in plots treated with triclopyr (20 ± 5%) compared with plots subjected to clipping-only (56 ± 6%) or unmanaged controls (76 ± 6%). Stem densities were also lower in triclopyr-treated plots (25 ± 5 stems/m2) than in clipping-only (188 ± 9 stems/m2) and control (178 ± 10 stems/m2) plots across three different sample dates. Seedling densities were lower in triclopyr-treated plots (160 ± 50 seedlings/m2) relative to clipping-only (1,120 ± 180 seedlings/m2) and control (960 ± 50 seedlings/m2) plots after the 2005 growing season. The cover of other plant species was negatively correlated with swallow-wort cover and was higher in triclopyr-treated plots (75 ± 3%) than in clipping-only (5 ± 1%) and control (7 ± 4%) plots in 2006. Across both years, swallow-wort in control and clipped plots produced follicles, but not in triclopyr-treated plots. Regardless of clipping frequency, clipping in June or July was not effective in reducing swallow-wort stem density, cover, or follicle production. Although a single application of triclopyr provided considerable suppression of swallow-wort after two growing seasons, application of triclopyr in subsequent years is likely required to achieve long-term control.